IKBIP Polyclonal Antibody

Specifications

Catalog number

E-AB-15128-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.

Abbreviation

IKBIP

UniProt

Q70UQ0

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human IKBIP

Target

FLJ31051; I kappa B kinase interacting protein; IKBIP; IKBKB interacting protein; IKIP1; IKIP2; IKIP3; IKK interacting protein; Inhibitor of nuclear factor kappa B kinase interacting protein

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cell Biology

Purification

Affinity purification

Concentration

0.4 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG