KDM3B Polyclonal Antibody

Catalog number E-AB-15146-01

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Price for E-AB-15146-01

Size / count 20 µL

Specifications

Catalog number: E-AB-15146-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.
Abbreviation: KDM3B
UniProt: Q7LBC6
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: Recombinant protein of human KDM3B
Target: 5qNCA; C5orf7; JHDM2B; JmjC domain containing histone demethylation protein 2B; JmjC domain-containing histone demethylation protein 2B; jmjd1b; Jumonji domain containing 1B; Jumonji domain containing protein 1B; Jumonji domain-containing protein 1B; KDM3B; KDM3B; KIAA1082; Lysine (K) specific demethylase 3B; Lysine-specific demethylase 3B; NET22; Nuclear protein 5qNCA
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Epigenetics and Nuclear Signaling
Purification: Affinity purification
Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for KDM3B Polyclonal Antibody?

The catalog number for KDM3B Polyclonal Antibody is E-AB-15146.

What sizes are available for KDM3B Polyclonal Antibody?

KDM3B Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does KDM3B Polyclonal Antibody come in?

KDM3B Polyclonal Antibody is available in 4 different pack sizes.

Is KDM3B Polyclonal Antibody in stock?

KDM3B Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures KDM3B Polyclonal Antibody?

KDM3B Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for KDM3B Polyclonal Antibody?

Estimated delivery time for KDM3B Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for KDM3B Polyclonal Antibody?

The safety data sheet for KDM3B Polyclonal Antibody is available here: https://789.bio/eb/rX1Oq5.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.