ADO Polyclonal Antibody

Catalog number E-AB-15460-01

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Price for E-AB-15460-01

Size / count 20 µL

Specifications

Catalog number: E-AB-15460-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Human thiol dioxygenases include cysteine dioxygenase (CDO, MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO, EC 1.13.11.19) . CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine. Mouse Ado has strong and specific dioxygenase activity in vitro towards cysteamine but not cysteine. Recombinant Ado was shown to bind iron. Overexpression of Ado in HepG2/C3A cells increased the production of hypotaurine from cysteamine. Similar results were found with human ADO. When endogenous expression of ADO was reduced by RNA-mediated interference, hypotaurine production decreased. The demonstration of high levels of ADO in brain challenges the previous assumption that most of the taurine in the brain is a consequence of CDO activity.
Abbreviation: ADO
UniProt: Q96SZ5
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: Synthetic peptide of human ADO
Target: 2 aminoethanethiol dioxygenase;2-aminoethanethiol dioxygenase; ADO 2 aminoethanethiol (cysteamine) dioxygenase; ADO; AEDO; C10orf22; Chromosome 10 open reasing frame 22; cysteamine (2-aminoethanethiol) dioxygenase (ADO) ; Cysteamine dioxygenase; DKFZp564C046; FLJ14547
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Metabolism; Signal Transduction
Purification: Affinity purification
Concentration: 0.3 mg/mL
Dilution: WB 1:1000-1:5000; IHC 1:25-1:100
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 30kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for ADO Polyclonal Antibody?

The catalog number for ADO Polyclonal Antibody is E-AB-15460.

What sizes are available for ADO Polyclonal Antibody?

ADO Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does ADO Polyclonal Antibody come in?

ADO Polyclonal Antibody is available in 4 different pack sizes.

Is ADO Polyclonal Antibody in stock?

ADO Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ADO Polyclonal Antibody?

ADO Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for ADO Polyclonal Antibody?

Estimated delivery time for ADO Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ADO Polyclonal Antibody?

The safety data sheet for ADO Polyclonal Antibody is available here: https://789.bio/eb/jzP0y5.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.