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Product details

AVEN Polyclonal Antibody

Catalog number E-AB-15518-01

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Price for E-AB-15518-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-15518-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1’s ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), AVEN expression may be a useful tool in prognosis prediction.
Abbreviation
AVEN
UniProt
Q9NQS1
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human AVEN
Target
1700013A01Rik;1700056A21Rik; Apoptosis caspase activation inhibitor; AVEN; AVEN; Cell death regulator Aven; mAven L; mAven S; MGC124011; OTTMUSP00000016129; PDCD12; Programmed cell death 12; RP23-52C15.2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
39kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for AVEN Polyclonal Antibody?

The catalog number for AVEN Polyclonal Antibody is E-AB-15518.

What sizes are available for AVEN Polyclonal Antibody?

AVEN Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does AVEN Polyclonal Antibody come in?

AVEN Polyclonal Antibody is available in 4 different pack sizes.

Is AVEN Polyclonal Antibody in stock?

AVEN Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AVEN Polyclonal Antibody?

AVEN Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for AVEN Polyclonal Antibody?

Estimated delivery time for AVEN Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AVEN Polyclonal Antibody?

The safety data sheet for AVEN Polyclonal Antibody is available here: https://789.bio/eb/OCWnLK.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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