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Product details

SLC1A6 Polyclonal Antibody

Catalog number E-AB-15608-01

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Price for E-AB-15608-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-15608-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
Abbreviation
SLC1A6
UniProt
P48664
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human SLC1A6
Target
Excitatory amino acid transporter 4; High affinity neuronal glutamate transporter; MGC33092; MGC43671; Sodium dependent glutamate/aspartate transporter; Solute carrier family 1 (high affinity aspartate/glutamate transporter) member 6; Solute carrier family 1 member 6
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
62kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for SLC1A6 Polyclonal Antibody?

The catalog number for SLC1A6 Polyclonal Antibody is E-AB-15608.

What sizes are available for SLC1A6 Polyclonal Antibody?

SLC1A6 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does SLC1A6 Polyclonal Antibody come in?

SLC1A6 Polyclonal Antibody is available in 4 different pack sizes.

Is SLC1A6 Polyclonal Antibody in stock?

SLC1A6 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SLC1A6 Polyclonal Antibody?

SLC1A6 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for SLC1A6 Polyclonal Antibody?

Estimated delivery time for SLC1A6 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SLC1A6 Polyclonal Antibody?

The safety data sheet for SLC1A6 Polyclonal Antibody is available here: https://789.bio/eb/GebrPO.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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