MC1R Polyclonal Antibody

Catalog number E-AB-15765-01

Choose a variant (4 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-15765-01

Size / count 20 µL

Specifications

Catalog number: E-AB-15765-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH) . The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation.
Abbreviation: MC1R
UniProt: Q01726
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: Synthetic peptide of human MC1R
Target: CMM5; MC1-R; MC1R; Melanocortin 1 receptor; Melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) ; Melanocortin receptor 1; Melanocyte-stimulating hormone receptor; Melanotropin receptor; MSH-R; MSHR; MSHR; SHEP2
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Metabolism; Neuroscience
Purification: Affinity purification
Concentration: 0.9 mg/mL
Dilution: IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01: https://www.frontiersin.org/articles/10.3389/fphys.2018.00172/full
Citation 02: https://anatomypubs.onlinelibrary.wiley.com/doi/abs/10.1002/ar.24934
Citation 03: https://link.springer.com/article/10.1134/S0022093022040263
Isotype: IgG

Frequently Asked Questions

What is the catalog number for MC1R Polyclonal Antibody?

The catalog number for MC1R Polyclonal Antibody is E-AB-15765.

What sizes are available for MC1R Polyclonal Antibody?

MC1R Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does MC1R Polyclonal Antibody come in?

MC1R Polyclonal Antibody is available in 4 different pack sizes.

Is MC1R Polyclonal Antibody in stock?

MC1R Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MC1R Polyclonal Antibody?

MC1R Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for MC1R Polyclonal Antibody?

Estimated delivery time for MC1R Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MC1R Polyclonal Antibody?

The safety data sheet for MC1R Polyclonal Antibody is available here: https://789.bio/eb/4y5y9C.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.