MMP25 Polyclonal Antibody

Catalog number E-AB-15779-01

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Price for E-AB-15779-01

Size / count 20 µL

Specifications

Catalog number: E-AB-15779-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
Abbreviation: MMP25
UniProt: Q9NPA2
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human MMP25
Target: Leukolysin; matrix metallopeptidase 25; matrix metallopeptidase like 1; matrix metalloproteinase 20; Matrix Metalloproteinase 25; Matrix metalloproteinase 25 precursor; Matrix metalloproteinase-25; Membrane type 6 Matrix Metalloproteinase; Membrane type Matrix Metalloproteinase 6; Membrane-type matrix metalloproteinase 6; Membrane-type-6 matrix metalloproteinase; MMP 25; MMP-25; MMP20; MMP20A; MMP25; MMP25; MMPL1; MT-MMP 6; MT6-MMP; MT6MMP; MTMMP6
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Cell Biology; Signal Transduction
Purification: Affinity purification
Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 63kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for MMP25 Polyclonal Antibody?

The catalog number for MMP25 Polyclonal Antibody is E-AB-15779.

What sizes are available for MMP25 Polyclonal Antibody?

MMP25 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does MMP25 Polyclonal Antibody come in?

MMP25 Polyclonal Antibody is available in 4 different pack sizes.

Is MMP25 Polyclonal Antibody in stock?

MMP25 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MMP25 Polyclonal Antibody?

MMP25 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for MMP25 Polyclonal Antibody?

Estimated delivery time for MMP25 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MMP25 Polyclonal Antibody?

The safety data sheet for MMP25 Polyclonal Antibody is available here: https://789.bio/eb/jH8uzH.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.