SHH Polyclonal Antibody

Catalog number E-AB-15842-01

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Price for E-AB-15842-01

Size / count 20 µL

Specifications

Catalog number: E-AB-15842-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities.
Abbreviation: SHH
UniProt: Q15465
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic peptide of human SHH
Target: HHG 1; HHG-1; HHG1; HLP 3; HLP3; Holoprosencephaly 3; HPE 3; HPE3; MCOPCB5; shh; SHH; SMMC I; SMMCI; Sonic Hedgehog (Drosophila) homolog; sonic hedgehog homolog (Drosophila) ; Sonic hedgehog homolog; Sonic hedgehog protein; Sonic hedgehog protein C-product; TPT; TPTPS
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Metabolism; Developmental Biology; Stem Cells
Purification: Affinity purification
Concentration: 0.8 mg/mL
Dilution: IHC 1:50-1:100
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for SHH Polyclonal Antibody?

The catalog number for SHH Polyclonal Antibody is E-AB-15842.

What sizes are available for SHH Polyclonal Antibody?

SHH Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does SHH Polyclonal Antibody come in?

SHH Polyclonal Antibody is available in 4 different pack sizes.

Is SHH Polyclonal Antibody in stock?

SHH Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SHH Polyclonal Antibody?

SHH Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for SHH Polyclonal Antibody?

Estimated delivery time for SHH Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SHH Polyclonal Antibody?

The safety data sheet for SHH Polyclonal Antibody is available here: https://789.bio/eb/b5yPyH.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.