TERT Polyclonal Antibody

Catalog number E-AB-16091-01

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Price for E-AB-16091-01

Size / count 20 µL

Specifications

Catalog number: E-AB-16091-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.
Abbreviation: TERT
UniProt: O14746
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human TERT
Target: CMM9; DKCA2; DKCB4; EST2; HEST2; htert; hTRT; PFBMFT1; TCS1; Telomerase associated protein 2; Telomerase catalytic subunit; Telomerase reverse transcriptase; Telomerase-associated protein 2; Telomere Reverse Transcriptase; TERT; TERT; TP2; TRT
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Developmental Biology; Stem Cells
Purification: Affinity purification
Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for TERT Polyclonal Antibody?

The catalog number for TERT Polyclonal Antibody is E-AB-16091.

What sizes are available for TERT Polyclonal Antibody?

TERT Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does TERT Polyclonal Antibody come in?

TERT Polyclonal Antibody is available in 4 different pack sizes.

Is TERT Polyclonal Antibody in stock?

TERT Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TERT Polyclonal Antibody?

TERT Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for TERT Polyclonal Antibody?

Estimated delivery time for TERT Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TERT Polyclonal Antibody?

The safety data sheet for TERT Polyclonal Antibody is available here: https://789.bio/eb/XrrbrH.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.