NSMCE3 Polyclonal Antibody

Specifications

Catalog number

E-AB-16215-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs) .

Abbreviation

NDNL2

UniProt

Q96MG7

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human NDNL2

Target

HCA4; hepatocellular carcinoma-associated protein 4; hepatocellular carcinoma-associated protein HCA4; MAGE-G1 antigen; MAGEG1; MAGEL3; melanoma antigen; family G;1; melanoma-associated antigen G1; necdin-like 2; necdin-like gene 2; necdin-like protein 2; NSE3; NSMCE3

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Immunology

Purification

Affinity purification

Concentration

1.4 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

34kDa

Isotype

IgG