ERN2 Polyclonal Antibody

Catalog number E-AB-16413-01

Choose a variant (4 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-16413-01

Size / count 20 µL

Specifications

Catalog number: E-AB-16413-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The accumulation of unfolded proteins within the endoplasmic recticulum (ER) of yeast and mammalian cells activates the unfolded protein response (UPR) pathway and leads to the transcription of ER-specific genes involved in protein folding. The activation of the UPR requires the ER transmembrane kinase IRE1p (for inositol-requiring and ER-to-nucleus signaling protein) . IRE1α and IRE1β are two mammalian homologs of the yeast IRE1p. These related proteins localize to the ER lumen and contain both a short transmembrane domain that spans the ER membrane and a cytosolic Ser/Thr kinase domain. IRE1 activation involves the oligomerization and trans-phosphorylation of the cytosolic portion of the proteins, which then potentiates its intrinsic kinase activity and, in turn, stimulates transcription of UPR-targeted genes.
Abbreviation: ERN2
UniProt: Q76MJ5
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human ERN2
Target: IRE1b; IRE1-BETA
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Signal Transduction
Purification: Affinity purification
Concentration: 1.1 mg/mL
Dilution: IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for ERN2 Polyclonal Antibody?

The catalog number for ERN2 Polyclonal Antibody is E-AB-16413.

What sizes are available for ERN2 Polyclonal Antibody?

ERN2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does ERN2 Polyclonal Antibody come in?

ERN2 Polyclonal Antibody is available in 4 different pack sizes.

Is ERN2 Polyclonal Antibody in stock?

ERN2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ERN2 Polyclonal Antibody?

ERN2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for ERN2 Polyclonal Antibody?

Estimated delivery time for ERN2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ERN2 Polyclonal Antibody?

The safety data sheet for ERN2 Polyclonal Antibody is available here: https://789.bio/eb/CKOu9C.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.