HSD17B1 Polyclonal Antibody

Catalog number E-AB-16497-01

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Price for E-AB-16497-01

Size / count 20 µL

Specifications

Catalog number: E-AB-16497-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP (H) over NAD (H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.
Abbreviation: HSD17B1
UniProt: P14061
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human HSD17B1
Target: 17 beta HSD 1;17 beta hydroxysteroid dehydrogenase type 1;17-beta-HSD 1;17-beta-hydroxysteroid dehydrogenase type 1;20 alpha-hydroxysteroid dehydrogenase;20-alpha-HSD; DHB1; E17KSR; E2DH; EDH17B1; EDH17B2; EDHB17; Estradiol 17 beta dehydrogenase 1; Estradiol 17-beta-dehydrogenase 1; HSD17; HSD17B1; Hydroxysteroid (17 beta) dehydrogenase 1; MGC13814; Placental 17 beta hydroxysteroid dehydrogenase; Placental 17-beta-hydroxysteroid dehydrogenase; SDR28C1; Short chain dehydrogenase/reductase family 28CE; member 1
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Metabolism; Neuroscience; Signal transduction
Purification: Affinity purification
Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:50-1:200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 35kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for HSD17B1 Polyclonal Antibody?

The catalog number for HSD17B1 Polyclonal Antibody is E-AB-16497.

What sizes are available for HSD17B1 Polyclonal Antibody?

HSD17B1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does HSD17B1 Polyclonal Antibody come in?

HSD17B1 Polyclonal Antibody is available in 4 different pack sizes.

Is HSD17B1 Polyclonal Antibody in stock?

HSD17B1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HSD17B1 Polyclonal Antibody?

HSD17B1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for HSD17B1 Polyclonal Antibody?

Estimated delivery time for HSD17B1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HSD17B1 Polyclonal Antibody?

The safety data sheet for HSD17B1 Polyclonal Antibody is available here: https://789.bio/eb/9SaPqT.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.