IL5RA Polyclonal Antibody

Specifications

Catalog number

E-AB-16515-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5) . The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

Abbreviation

IL5RA

UniProt

Q01344

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human IL5RA

Target

CD125; CD125 antigen; CDw125; HSIL5R3; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; IL5R; IL5RA; IL5RA; Interleukin 5 Receptor alpha; Interleukin 5 Receptor alpha chain; Interleukin 5 receptor alpha subunit; Interleukin 5 receptor subunit alpha; Interleukin 5 receptor type 3; Interleukin-5 receptor subunit alpha; MGC26560

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Immunology

Purification

Affinity purification

Concentration

0.9 mg/mL

Dilution

WB 1:200-1:1000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

48kDa

Isotype

IgG