SMAD4 Polyclonal Antibody — image 1 of 2

Product details

SMAD4 Polyclonal Antibody

Catalog number E-AB-16957-01

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Price for E-AB-16957-01

Size / count 20 µL

Specifications

Catalog number: E-AB-16957-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE) . The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.
Abbreviation: SMAD4
UniProt: Q13485
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Fusion protein of human SMAD4
Target: JIP; DPC4; MADH4; MYHRS
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Signal transduction; Stem cells
Purification: Affinity purification
Concentration: 0.5 mg/mL
Dilution: IHC 1:50-200
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 60 kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for SMAD4 Polyclonal Antibody?

The catalog number for SMAD4 Polyclonal Antibody is E-AB-16957.

What sizes are available for SMAD4 Polyclonal Antibody?

SMAD4 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does SMAD4 Polyclonal Antibody come in?

SMAD4 Polyclonal Antibody is available in 4 different pack sizes.

Is SMAD4 Polyclonal Antibody in stock?

SMAD4 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SMAD4 Polyclonal Antibody?

SMAD4 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for SMAD4 Polyclonal Antibody?

Estimated delivery time for SMAD4 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SMAD4 Polyclonal Antibody?

The safety data sheet for SMAD4 Polyclonal Antibody is available here: https://789.bio/eb/C0eLS4.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.