INHBB Polyclonal Antibody

Specifications

Catalog number

E-AB-17341-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Abbreviation

INHBB

UniProt

P09529

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human INHBB

Target

Activin beta B chain; Activin beta-B chain; INHBB; INHBB; Inhibin beta 2; Inhibin beta B chain; Inhibin beta B subunit

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Neuroscience; Signal transduction

Purification

Affinity purification

Concentration

0.8 mg/mL

Dilution

IHC 1:30-150

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG