IRS2 Polyclonal Antibody

Specifications

Catalog number

E-AB-17345-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

Abbreviation

IRS2

UniProt

Q9Y4H2

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human IRS2

Target

Insulin receptor substrate 2; IRS 2; IRS-2; Irs2; IRS2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cardiovascular; Metabolism; Signal transduction

Purification

Affinity purification

Concentration

0.6 mg/mL

Dilution

IHC 1:50-200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG