DMTN Polyclonal Antibody

Catalog number E-AB-17886-01

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Price for E-AB-17886-01

Size / count 20 µL

Specifications

Catalog number: E-AB-17886-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms. DMTN (Dematin Actin Binding Protein) is a Protein Coding gene. Diseases associated with DMTN include Hypotrichosis and Hereditary Spherocytosis. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Miscellaneous transport and binding events. GO annotations related to this gene include receptor binding and protein self-association. An important paralog of this gene is ABLIM1.
Abbreviation: DMTN
UniProt: Q08495
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: Synthetic peptide of human DMTN
Target: DEMA; DEMA; Dematin; DMT; EPB49; erythrocyte membrane protein band 4.9 (dematin) ; Erythrocyte membrane protein band 4.9
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Signal Transduction
Purification: Antigen affinity purification
Concentration: 1.5 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:20-1:100
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 46 kDa
Observed Molecular Weight: Refer to figures
Isotype: IgG

Frequently Asked Questions

What is the catalog number for DMTN Polyclonal Antibody?

The catalog number for DMTN Polyclonal Antibody is E-AB-17886.

What sizes are available for DMTN Polyclonal Antibody?

DMTN Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does DMTN Polyclonal Antibody come in?

DMTN Polyclonal Antibody is available in 4 different pack sizes.

Is DMTN Polyclonal Antibody in stock?

DMTN Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DMTN Polyclonal Antibody?

DMTN Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for DMTN Polyclonal Antibody?

Estimated delivery time for DMTN Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DMTN Polyclonal Antibody?

The safety data sheet for DMTN Polyclonal Antibody is available here: https://789.bio/eb/1GGKq5.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.