HLA-B Polyclonal Antibody

Catalog number E-AB-17921-01

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Price for E-AB-17921-01

Size / count 20 µL

Specifications

Catalog number: E-AB-17921-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin) . The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
Abbreviation: HLA-B
UniProt: P01889
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human HLA-B
Target: 1B07; AS; B-4901; B-7 alpha chain; HC class I antigen SHCHA; HLA class I histocompatibility antigen; HLA class I histocompatibility antigen; B alpha chain; HLA-B; HLA-B histocompatibility type; HLAB; leukocyte antigen class I-B; major histocompatibility complex; class I; B; MHC class 1 antigen; MHC class I antigen B*7; MHC class I antigen HLA-B alpha chain; MHC class I antigen HLA-B heavy chain; MHC Class I HLA heavy chain; MHC class I molecule; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; SPDA1
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Immunology; Microbiology
Purification: Antigen affinity purification
Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:30-1:150
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 40 kDa
Observed Molecular Weight: Refer to figures
Isotype: IgG

Frequently Asked Questions

What is the catalog number for HLA-B Polyclonal Antibody?

The catalog number for HLA-B Polyclonal Antibody is E-AB-17921.

What sizes are available for HLA-B Polyclonal Antibody?

HLA-B Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does HLA-B Polyclonal Antibody come in?

HLA-B Polyclonal Antibody is available in 4 different pack sizes.

Is HLA-B Polyclonal Antibody in stock?

HLA-B Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-B Polyclonal Antibody?

HLA-B Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for HLA-B Polyclonal Antibody?

Estimated delivery time for HLA-B Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-B Polyclonal Antibody?

The safety data sheet for HLA-B Polyclonal Antibody is available here: https://789.bio/eb/vrz1mT.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.