HLA-C Polyclonal Antibody

Catalog number E-AB-17922-01

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Price for E-AB-17922-01

Size / count 20 µL

Specifications

Catalog number: E-AB-17922-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin) . The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described .
Abbreviation: HLA-C
UniProt: P10321
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human HLA-C
Target: HLA-JY3; D6S204; HLAC; Psoriasis Susceptibility 1; HLA-C Alpha Chain; PSORS1; MHC
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Immunology; Microbiology
Purification: Antigen affinity purification
Concentration: 0.66 mg/mL
Dilution: IHC 1:25-1:100
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01: https://www.nature.com/articles/s41598-022-12870-6
Isotype: IgG

Frequently Asked Questions

What is the catalog number for HLA-C Polyclonal Antibody?

The catalog number for HLA-C Polyclonal Antibody is E-AB-17922.

What sizes are available for HLA-C Polyclonal Antibody?

HLA-C Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does HLA-C Polyclonal Antibody come in?

HLA-C Polyclonal Antibody is available in 4 different pack sizes.

Is HLA-C Polyclonal Antibody in stock?

HLA-C Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-C Polyclonal Antibody?

HLA-C Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for HLA-C Polyclonal Antibody?

Estimated delivery time for HLA-C Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-C Polyclonal Antibody?

The safety data sheet for HLA-C Polyclonal Antibody is available here: https://789.bio/eb/aLqPaH.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.