IRGC Polyclonal Antibody

Catalog number E-AB-18127-01

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Price for E-AB-18127-01

Size / count 20 µL

Specifications

Catalog number: E-AB-18127-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans. Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs. In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines. As the two human genes IRGC and IRGM are not subject to IFN control, it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans.
Abbreviation: IRGC
UniProt: Q6NXR0
Host: Rabbit
Reactivity: Human; Rat
Immunogen: Synthetic peptide of human IRGC
Target: F630044M05Rik; Gm1102; Gm474; IIGP5; IIGP5; Immunity-related GTPase cinema 1; Interferon-inducible GTPase 5; IRGC; IRGC1; RGD1311107
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cell Biology; Signal transduction
Purification: Antigen affinity purification
Concentration: 0.78 mg/mL
Dilution: IHC 1:30-1:150
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for IRGC Polyclonal Antibody?

The catalog number for IRGC Polyclonal Antibody is E-AB-18127.

What sizes are available for IRGC Polyclonal Antibody?

IRGC Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does IRGC Polyclonal Antibody come in?

IRGC Polyclonal Antibody is available in 4 different pack sizes.

Is IRGC Polyclonal Antibody in stock?

IRGC Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IRGC Polyclonal Antibody?

IRGC Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for IRGC Polyclonal Antibody?

Estimated delivery time for IRGC Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for IRGC Polyclonal Antibody?

The safety data sheet for IRGC Polyclonal Antibody is available here: https://789.bio/eb/KuXzf1.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.