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Product details

CREBBP Polyclonal Antibody

Catalog number E-AB-18158-01

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Price for E-AB-18158-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-18158-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS) . Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Abbreviation
CREBBP
UniProt
Q92793
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human CREBBP
Target
CBP; CBP; CREB binding protein; CREB-binding protein; Crebbp; Cyclic AMP responsive enhancer binding protein; KAT3A; RSTS; RTS; Rubinstein Taybi syndrome
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Metabolism; Microbiology; Stem Cells
Purification
Antigen affinity purification
Concentration
1.02 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for CREBBP Polyclonal Antibody?

The catalog number for CREBBP Polyclonal Antibody is E-AB-18158.

What sizes are available for CREBBP Polyclonal Antibody?

CREBBP Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does CREBBP Polyclonal Antibody come in?

CREBBP Polyclonal Antibody is available in 4 different pack sizes.

Is CREBBP Polyclonal Antibody in stock?

CREBBP Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CREBBP Polyclonal Antibody?

CREBBP Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CREBBP Polyclonal Antibody?

Estimated delivery time for CREBBP Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CREBBP Polyclonal Antibody?

The safety data sheet for CREBBP Polyclonal Antibody is available here: https://789.bio/eb/WPaPqH.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

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