KIR2DL5A Polyclonal Antibody

Catalog number E-AB-18184-01

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Price for E-AB-18184-01

Size / count 20 µL

Specifications

Catalog number: E-AB-18184-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC) . The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2) . The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
Abbreviation: KIR2DL5A
UniProt: Q8N109
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human KIR2DL5A
Target: CD158F; CD158f1; KI2LA; Killer cell immunoglobulin-like receptor 2DL5A; killer cell immunoglobulin-like receptor KIR2DL5A; killer cell immunoglobulin-like receptor; two domains; long cytoplasmic tail; 5; killer cell immunoglobulin-like receptor; two domains; long cytoplasmic tail; 5A; killer-cell Ig-like receptor; KIR2DL5; KIR2DL5.1; KIR2DL5.3; KIR2DL5A; KIR2DL5B
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Purification: Antigen affinity purification
Concentration: 1.2 mg/mL
Dilution: WB 1:1000-1:5000; IHC 1:40-1:200
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 41 kDa
Observed Molecular Weight: Refer to figures
Isotype: IgG

Frequently Asked Questions

What is the catalog number for KIR2DL5A Polyclonal Antibody?

The catalog number for KIR2DL5A Polyclonal Antibody is E-AB-18184.

What sizes are available for KIR2DL5A Polyclonal Antibody?

KIR2DL5A Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does KIR2DL5A Polyclonal Antibody come in?

KIR2DL5A Polyclonal Antibody is available in 4 different pack sizes.

Is KIR2DL5A Polyclonal Antibody in stock?

KIR2DL5A Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures KIR2DL5A Polyclonal Antibody?

KIR2DL5A Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for KIR2DL5A Polyclonal Antibody?

Estimated delivery time for KIR2DL5A Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for KIR2DL5A Polyclonal Antibody?

The safety data sheet for KIR2DL5A Polyclonal Antibody is available here: https://789.bio/eb/W1a904.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.