PCNA Polyclonal Antibody

Catalog number E-AB-18205-01

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Price for E-AB-18205-01

Size / count 20 µL

Specifications

Catalog number: E-AB-18205-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase δ in eukaryotic cells. This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. PCNA induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. It has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA protein is highly conserved during evolution; the deduced amino acid sequences of rat and human differ by only 4 of 261 amino acids. PCNA has been used as loading control for proliferating cells.
Abbreviation: PCNA
UniProt: P12004
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Fusion protein of human PCNA
Target: ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; Pcna/cyclin; PCNA; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Tags and Cell Markers
Purification: Antigen affinity purification
Concentration: 0.7 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:25-1:100
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 29 kDa
Observed Molecular Weight: Refer to figures
Isotype: IgG

Frequently Asked Questions

What is the catalog number for PCNA Polyclonal Antibody?

The catalog number for PCNA Polyclonal Antibody is E-AB-18205.

What sizes are available for PCNA Polyclonal Antibody?

PCNA Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does PCNA Polyclonal Antibody come in?

PCNA Polyclonal Antibody is available in 4 different pack sizes.

Is PCNA Polyclonal Antibody in stock?

PCNA Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PCNA Polyclonal Antibody?

PCNA Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for PCNA Polyclonal Antibody?

Estimated delivery time for PCNA Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PCNA Polyclonal Antibody?

The safety data sheet for PCNA Polyclonal Antibody is available here: https://789.bio/eb/9iDivD.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.