RASA1 Polyclonal Antibody

Catalog number E-AB-18279-01

Choose a variant (4 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-18279-01

Size / count 20 µL

Specifications

Catalog number: E-AB-18279-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.
Abbreviation: RASA1
UniProt: P20936
Host: Rabbit
Reactivity: Human; Rat
Immunogen: Fusion protein of human RASA1
Target: CM AVM; CMAVM; DKFZp434N071; GAP; GTPase activating protein; GTPase-activating protein; OTTHUMP00000222390; OTTHUMP00000222391; OTTHUMP00000222392; OTTHUMP00000222393; p120GAP; p120RASGAP; PKWS; Ras GTPase-activating protein 1; RAS p21 protein activator (GTPase activating protein) 1; Ras p21 protein activator; RASA; RASA1; RASA1; RasGAP; Triphosphatase activating protein
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Signal transduction
Purification: Antigen affinity purification
Concentration: 0.5 mg/mL
Dilution: IHC 1:30-1:150
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for RASA1 Polyclonal Antibody?

The catalog number for RASA1 Polyclonal Antibody is E-AB-18279.

What sizes are available for RASA1 Polyclonal Antibody?

RASA1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does RASA1 Polyclonal Antibody come in?

RASA1 Polyclonal Antibody is available in 4 different pack sizes.

Is RASA1 Polyclonal Antibody in stock?

RASA1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RASA1 Polyclonal Antibody?

RASA1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for RASA1 Polyclonal Antibody?

Estimated delivery time for RASA1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for RASA1 Polyclonal Antibody?

The safety data sheet for RASA1 Polyclonal Antibody is available here: https://789.bio/eb/fz58OC.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.