Product details

TPPP Polyclonal Antibody

Catalog number E-AB-18394-01

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Price for E-AB-18394-01

Size / count 20 µL

Specifications

Catalog number: E-AB-18394-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
Abbreviation: TPPP
UniProt: O94811
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: Full length fusion protein
Target: 25 kDa brain specific protein ;25 kDa brain-specific protein; Brain specific protein p25 alpha; Glycogen synthase kinase 3 (GSK3) inhibitor p24; OTTHUMP00000161630; p24; p25; p25-alpha; p25alpha ; TPPP; TPPP/p25; TPPP; TPPP1; Tubulin polymerization promoting protein; Tubulin polymerization-promoting protein
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Signal transduction
Purification: Antigen affinity purification
Concentration: 0.8 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:25-1:100
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 24 kDa
Observed Molecular Weight: Refer to figures
Isotype: IgG

Frequently Asked Questions

What is the catalog number for TPPP Polyclonal Antibody?

The catalog number for TPPP Polyclonal Antibody is E-AB-18394.

What sizes are available for TPPP Polyclonal Antibody?

TPPP Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does TPPP Polyclonal Antibody come in?

TPPP Polyclonal Antibody is available in 4 different pack sizes.

Is TPPP Polyclonal Antibody in stock?

TPPP Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TPPP Polyclonal Antibody?

TPPP Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for TPPP Polyclonal Antibody?

Estimated delivery time for TPPP Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TPPP Polyclonal Antibody?

The safety data sheet for TPPP Polyclonal Antibody is available here: https://789.bio/eb/L8iL8O.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.