CASR Polyclonal Antibody

Catalog number E-AB-18582-01

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Price for E-AB-18582-01

Size / count 20 µL

Specifications

Catalog number: E-AB-18582-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: CASR (Calcium Sensing Receptor) is a Protein Coding gene. Diseases associated with CASR include Hypocalcemia, Autosomal Dominant and Hyperparathyroidism, Neonatal. Among its related pathways are Proton Pump Inhibitor Pathway, Pharmacodynamics and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and protein kinase binding. An important paralog of this gene is GPRC6A.The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH) -producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
Abbreviation: CASR
UniProt: P41180
Host: Rabbit
Reactivity: Human
Immunogen: Fusion protein of human CASR
Target: Ca sensing receptor; Ca2+ sensing receptor 1; Ca2+ sensing receptor; Calcium sensing receptor; CAR; CaSR; CASR; EIG8; Extracellular calcium sensing receptor; Extracellular calcium sensing receptor [Precursor]; Extracellular calcium-sensing receptor; FHH; FIH; GPRC2A; HHC; HHC1; Hypocalciuric hypercalcemia 1; Hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism; MGC138441; NSHPT; Parathyroid Ca (2+) sensing receptor 1; Parathyroid Cell calcium sensing receptor; Parathyroid Cell calcium-sensing receptor; PCAR 1; PCaR1
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Metabolism; Neuroscience; Signal Transduction
Purification: Antigen affinity purification
Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:300
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for CASR Polyclonal Antibody?

The catalog number for CASR Polyclonal Antibody is E-AB-18582.

What sizes are available for CASR Polyclonal Antibody?

CASR Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does CASR Polyclonal Antibody come in?

CASR Polyclonal Antibody is available in 4 different pack sizes.

Is CASR Polyclonal Antibody in stock?

CASR Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CASR Polyclonal Antibody?

CASR Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CASR Polyclonal Antibody?

Estimated delivery time for CASR Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CASR Polyclonal Antibody?

The safety data sheet for CASR Polyclonal Antibody is available here: https://789.bio/eb/LGenfD.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.