COMT Polyclonal Antibody

Catalog number E-AB-18664-01

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Price for E-AB-18664-01

Size / count 20 µL

Specifications

Catalog number: E-AB-18664-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT) . The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
Abbreviation: COMT
UniProt: P21964
Host: Rabbit
Reactivity: Human
Immunogen: Fusion protein of human COMT
Target: Catechol O methyltransferase; Catechol O-methyltransferase; COMT; COMT; EC 2.1.1.6
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Metabolism; Neuroscience; Signal transduction
Purification: Antigen affinity purification
Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:25-1:100
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 30 kDa
Observed Molecular Weight: Refer to figures
Isotype: IgG

Frequently Asked Questions

What is the catalog number for COMT Polyclonal Antibody?

The catalog number for COMT Polyclonal Antibody is E-AB-18664.

What sizes are available for COMT Polyclonal Antibody?

COMT Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does COMT Polyclonal Antibody come in?

COMT Polyclonal Antibody is available in 4 different pack sizes.

Is COMT Polyclonal Antibody in stock?

COMT Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures COMT Polyclonal Antibody?

COMT Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for COMT Polyclonal Antibody?

Estimated delivery time for COMT Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for COMT Polyclonal Antibody?

The safety data sheet for COMT Polyclonal Antibody is available here: https://789.bio/eb/Ca1mrD.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.