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Product details

IMPA1 Polyclonal Antibody

Catalog number E-AB-18668-01

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Price for E-AB-18668-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-18668-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.
Abbreviation
IMPA1
UniProt
P29218
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human IMPA1
Target
IMP 1; IMP; IMPA 1; IMPA; IMPA1; IMPA1; IMPase 1; IMPase; Inositol 1 (or 4) monophosphatase; Inositol monophosphatase 1; Inositol monophosphatase; Inositol (myo) 1 (or 4) monophosphatase 1; Inositol-1 (or 4) -monophosphatase 1; Lithium sensitive myo inositol monophosphatase A1; Lithium-sensitive myo-inositol monophosphatase A1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Neuroscience; Signal transduction
Purification
Antigen affinity purification
Concentration
0.9 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
30 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

Frequently Asked Questions

What is the catalog number for IMPA1 Polyclonal Antibody?

The catalog number for IMPA1 Polyclonal Antibody is E-AB-18668.

What sizes are available for IMPA1 Polyclonal Antibody?

IMPA1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does IMPA1 Polyclonal Antibody come in?

IMPA1 Polyclonal Antibody is available in 4 different pack sizes.

Is IMPA1 Polyclonal Antibody in stock?

IMPA1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IMPA1 Polyclonal Antibody?

IMPA1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for IMPA1 Polyclonal Antibody?

Estimated delivery time for IMPA1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for IMPA1 Polyclonal Antibody?

The safety data sheet for IMPA1 Polyclonal Antibody is available here: https://789.bio/eb/DGunH0.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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