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Product details

BCAS3 Polyclonal Antibody

Catalog number E-AB-18703-01

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Price for E-AB-18703-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-18703-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
BCAS3 (breast carcinoma amplified sequence 3), also designated MAAB or GAOB1, is a 913 amino acid protein that is believed to be involved in breast cancer progression. The gene is regulated by ER (estrogen receptor alpha) and expressed in multiple tissues, including malignant human brain lesions. It is overexpressed and amplified in breast cancer cell lines. BCAS3 contains three WD40 repeat regions, a bromodomain, a rare zinc-finger motif, four probable DNA-binding domains, and two kinase-inducible phosphorylation domains. Five variants are produced due to alternative splicing. BCAS3 interacts with histone H3 and PCAF, which is indicative of histone acetyltransferase activity. BCAS3 also exhibits ER transactiviation activity by acting as a coactivator with PELP1 or MTA1. The amplification and translocation between the BCAS3 gene and the BCAS4 gene results in a fusion transcript is overexpressed in MCF-7 cells.
Abbreviation
BCAS3
UniProt
Q9H6U6
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human BCAS3
Target
1500019F07Rik;2610028P08Rik; AU021018; BC028339; BCAS3; BCAS3; Breast carcinoma-amplified sequence 3; FLJ20128; GAOB1; K20D4; MAAB; Maab1 protein; MGC4973; rudhira
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Stem Cells
Purification
Antigen affinity purification
Concentration
1.26 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
101 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

Frequently Asked Questions

What is the catalog number for BCAS3 Polyclonal Antibody?

The catalog number for BCAS3 Polyclonal Antibody is E-AB-18703.

What sizes are available for BCAS3 Polyclonal Antibody?

BCAS3 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does BCAS3 Polyclonal Antibody come in?

BCAS3 Polyclonal Antibody is available in 4 different pack sizes.

Is BCAS3 Polyclonal Antibody in stock?

BCAS3 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BCAS3 Polyclonal Antibody?

BCAS3 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for BCAS3 Polyclonal Antibody?

Estimated delivery time for BCAS3 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BCAS3 Polyclonal Antibody?

The safety data sheet for BCAS3 Polyclonal Antibody is available here: https://789.bio/eb/X1in9K.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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