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Product details

RNF111 Polyclonal Antibody

Catalog number E-AB-18773-01

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Price for E-AB-18773-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-18773-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Abbreviation
RNF111
UniProt
Q6ZNA4
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human RNF111
Target
ARK; Arkadia; DKFZp313E0731; DKFZp686H1966; DKFZp761D081; E3 ubiquitin protein ligase Arkadia; E3 ubiquitin-protein ligase Arkadia; FLJ38008; RING finger protein 111; RN111; RNF 111; RNF111
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Signal transduction
Purification
Antigen affinity purification
Concentration
0.84 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for RNF111 Polyclonal Antibody?

The catalog number for RNF111 Polyclonal Antibody is E-AB-18773.

What sizes are available for RNF111 Polyclonal Antibody?

RNF111 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does RNF111 Polyclonal Antibody come in?

RNF111 Polyclonal Antibody is available in 4 different pack sizes.

Is RNF111 Polyclonal Antibody in stock?

RNF111 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RNF111 Polyclonal Antibody?

RNF111 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for RNF111 Polyclonal Antibody?

Estimated delivery time for RNF111 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for RNF111 Polyclonal Antibody?

The safety data sheet for RNF111 Polyclonal Antibody is available here: https://789.bio/eb/08ajH4.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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