CALCOCO1 Polyclonal Antibody

Specifications

Catalog number

E-AB-18858-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/β-catenin signaling pathway. CALCOCO1 exists as three alternatively spliced isoforms (termed Q9P1Z2-1, 2 and 3), which are encoded by genes mapping to human chromosome 12q13.13 and mouse chromosome 15 F3.

Abbreviation

CALCOCO1

UniProt

Q9P1Z2

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human CALCOCO1

Target

Calcium binding and coiled coil domain 1; CALCOCO1; Calphoglin ; Coiled coil coactivator protein; Coiled coil leucine zipper coactivator 1 ; Coiled coil transcriptional coactivator ; Inorganic pyrophosphatase activator ; KIAA1536 ; PP13275 ; Sarcoma antigen NY-SAR-3

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling; Signal transduction

Purification

Antigen affinity purification

Concentration

0.84 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:40-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

77 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG