NGEF Polyclonal Antibody

Catalog number E-AB-18859-01

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Price for E-AB-18859-01

Size / count 20 µL

Specifications

Catalog number: E-AB-18859-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity) .
Abbreviation: NGEF
UniProt: Q8N5V2
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Fusion protein of human NGEF
Target: ARHGEF27; Eph receptor-interacting exchange protein; Eph-interacting exchange protein; EPHEXIN; Ephexin-1; Guanine nucleotide exchange factor; neuronal; Neuronal guanine nucleotide exchange factor; Ngef; NGEF
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Neuroscience; Signal transduction
Purification: Antigen affinity purification
Concentration: 0.6 mg/mL
Dilution: IHC 1:40-1:200
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for NGEF Polyclonal Antibody?

The catalog number for NGEF Polyclonal Antibody is E-AB-18859.

What sizes are available for NGEF Polyclonal Antibody?

NGEF Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does NGEF Polyclonal Antibody come in?

NGEF Polyclonal Antibody is available in 4 different pack sizes.

Is NGEF Polyclonal Antibody in stock?

NGEF Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NGEF Polyclonal Antibody?

NGEF Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for NGEF Polyclonal Antibody?

Estimated delivery time for NGEF Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NGEF Polyclonal Antibody?

The safety data sheet for NGEF Polyclonal Antibody is available here: https://789.bio/eb/HSmjPG.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.