SLC26A3 Polyclonal Antibody

Specifications

Catalog number

E-AB-18861-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.SLC26A3 (Solute Carrier Family 26 Member 3) is a Protein Coding gene. Diseases associated with SLC26A3 include Diarrhea 1, Secretory Chloride, Congenital and Congenital Chloride Diarrhea. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Pancreatic secretion. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription cofactor activity. An important paralog of this gene is SLC26A4.

Abbreviation

SLC26A3

UniProt

P40879

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human SLC26A3

Target

Chloride anion exchanger; CLD; Congenital chloride diarrhea; Down regulated in adenoma; Down regulated in adenoma protein; Down-regulated in adenoma; DRA; Protein DRA; S26A3; SLC26A3; Solute carrier family 26 member 3

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Metabolism; Signal Transduction

Purification

Antigen affinity purification

Concentration

0.6 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

85 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG