PER3 Polyclonal Antibody

Specifications

Catalog number

E-AB-19010-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Abbreviation

PER3

UniProt

P56645

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human PER3

Target

2810049O06Rik ; Cell growth inhibiting gene 13 protein; Cell growth-inhibiting gene 13 protein; Circadian clock protein PERIOD 3; GIG13; gPER3; Growth inhibiting protein 13; HGNC:8847; hPER3; mPer3; Per3; PER3; Period 3; Period circadian clock 3; Period circadian protein 3; Period circadian protein homolog 3; Period homolog 3 (Drosophila) ; Period homolog 3; Period homolog 3; Drosophila; Period3

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cardiovascular; Epigenetics and Nuclear Signaling

Purification

Antigen affinity purification

Concentration

0.96 mg/mL

Dilution

IHC 1:50-1:300

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG