KPNA2 Polyclonal Antibody

Catalog number E-AB-19069-01

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Price for E-AB-19069-01

Size / count 20 µL

Specifications

Catalog number: E-AB-19069-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V (D) J recombination. Alternative splicing results in multiple transcript variants.
Abbreviation: KPNA2
UniProt: P52292
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: Fusion protein of human KPNA2
Target: IMA1; Importin alpha 1; Importin alpha 2; Importin alpha 2 subunit; Importin alpha P1; Importin subunit alpha-1; IPO A1; IPOA 1; IPOA1; Karyopherin alpha 2; Karyopherin alpha 2 RAG cohort 1; Karyopherin alpha 2 subunit; Karyopherin subunit alpha-2; KPNA2; KPNA2 protein; Pendulin; QIP 2; QIP2; RAG cohort 1; RAG cohort protein 1; RCH 1; RCH1; SRP 1; SRP1 alpha; SRP1; SRP1-alpha; SRP1alpha
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Immunology; Signal Transduction
Purification: Antigen affinity purification
Concentration: 1.5 mg/mL
Dilution: WB 1:1000-1:5000; IHC 1:50-1:300
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 58 kDa
Observed Molecular Weight: Refer to figures
Isotype: IgG

Frequently Asked Questions

What is the catalog number for KPNA2 Polyclonal Antibody?

The catalog number for KPNA2 Polyclonal Antibody is E-AB-19069.

What sizes are available for KPNA2 Polyclonal Antibody?

KPNA2 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does KPNA2 Polyclonal Antibody come in?

KPNA2 Polyclonal Antibody is available in 4 different pack sizes.

Is KPNA2 Polyclonal Antibody in stock?

KPNA2 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures KPNA2 Polyclonal Antibody?

KPNA2 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for KPNA2 Polyclonal Antibody?

Estimated delivery time for KPNA2 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for KPNA2 Polyclonal Antibody?

The safety data sheet for KPNA2 Polyclonal Antibody is available here: https://789.bio/eb/HmvLOK.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.