PAX5 Polyclonal Antibody

Specifications

Catalog number

E-AB-19303-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

PAX5, also named B-cell specific activator protein (BSAP), is a member of the highly conserved paired box (PAX) -domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B, pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL (B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL, PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members.

Abbreviation

PAX5

UniProt

Q02548

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human PAX5

Target

B cell lineage specific activator; B cell lineage specific activator protein; B cell specific activator protein; B cell specific transcription factor; B-cell-specific transcription factor; BSAP; EBB-1; KLP; Paired box 5; Paired box gene 5 (B cell lineage specific activator protein) ; Paired box gene 5 (B cell lineage specific activator) ; Paired box gene 5; Paired box homeotic gene 5; Paired box protein Pax 5; Paired box protein Pax-5; Paired domain gene 5; PAX 5; PAX5; PAX5; Transcription factor PAX 5

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Epigenetics and Nuclear Signaling; Neuroscience

Purification

Antigen affinity purification

Concentration

0.84 mg/mL

Dilution

IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG