VEGFA Polyclonal Antibody

Catalog number E-AB-19306-01

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Price for E-AB-19306-01

Size / count 20 µL

Specifications

Catalog number: E-AB-19306-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.
Abbreviation: VEGFA
UniProt: P15692
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human VEGFA
Target: Folliculostellate cell-derived growth factor; Glioma-derived endothelial cell mitogen; MGC70609; MVCD1; Vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor; Vascular permeability factor; VEGF A; Vegf; VEGF-A; VEGF120; Vegfa; VEGFA; VPF
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Cardiovascular; Metabolism; Developmental Biology; Signal Transduction
Purification: Antigen affinity purification
Concentration: 1.32 mg/mL
Dilution: WB 1:1000-1:5000; IHC 1:25-1:100
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 27 kDa
Observed Molecular Weight: Refer to figures
Citation 01: https://onlinelibrary.wiley.com/doi/abs/10.1111/aji.13589
Isotype: IgG

Frequently Asked Questions

What is the catalog number for VEGFA Polyclonal Antibody?

The catalog number for VEGFA Polyclonal Antibody is E-AB-19306.

What sizes are available for VEGFA Polyclonal Antibody?

VEGFA Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does VEGFA Polyclonal Antibody come in?

VEGFA Polyclonal Antibody is available in 4 different pack sizes.

Is VEGFA Polyclonal Antibody in stock?

VEGFA Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures VEGFA Polyclonal Antibody?

VEGFA Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for VEGFA Polyclonal Antibody?

Estimated delivery time for VEGFA Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for VEGFA Polyclonal Antibody?

The safety data sheet for VEGFA Polyclonal Antibody is available here: https://789.bio/eb/G088SG.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.