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Product details

HUWE1 Polyclonal Antibody

Catalog number E-AB-19540-01

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Price for E-AB-19540-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-19540-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related) ) . This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
Abbreviation
HUWE1
UniProt
Q7Z6Z7
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human HUWE1
Target
ARF binding protein 1; ARF BP1; ARF-binding protein 1; ARF-BP1; BJ-HCC-24 tumor antigen; E3 ubiquitin protein ligase HUWE1; E3 ubiquitin-protein ligase HUWE1; HECT; HECT domain protein LASU1; HECT UBA and WWE domain containing protein 1; HectH9; Homologous to E6AP carboxyl terminus homologous protein 9; Huwe1; HUWE1; Ib772; Large structure of UREB1; LASU1; Mcl 1 ubiquitin ligase E3; Mcl-1 ubiquitin ligase E3; Mule; UBA and WWE domain-containing protein 1; Upstream regulatory element-binding protein 1; URE-B1; URE-binding protein 1; UREB1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology
Purification
Antigen affinity purification
Concentration
0.8 mg/mL
Dilution
IHC 1:10-1:50
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for HUWE1 Polyclonal Antibody?

The catalog number for HUWE1 Polyclonal Antibody is E-AB-19540.

What sizes are available for HUWE1 Polyclonal Antibody?

HUWE1 Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does HUWE1 Polyclonal Antibody come in?

HUWE1 Polyclonal Antibody is available in 4 different pack sizes.

Is HUWE1 Polyclonal Antibody in stock?

HUWE1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HUWE1 Polyclonal Antibody?

HUWE1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for HUWE1 Polyclonal Antibody?

Estimated delivery time for HUWE1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HUWE1 Polyclonal Antibody?

The safety data sheet for HUWE1 Polyclonal Antibody is available here: https://789.bio/eb/LKiXLC.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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