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Product details

ATRX Polyclonal Antibody

Catalog number E-AB-19609-01

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Price for E-AB-19609-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-19609-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Abbreviation
ATRX
UniProt
P46100
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human ATRX
Target
Alpha thalassemia/mental retardation syndrome X linked homolog; ATP dependent helicase ATRX; ATP-dependent helicase ATRX; ATR2; Atrx; ATRX; DNA dependent ATPase and helicase; Helicase 2; X linked; MGC2094; MRXHF1; RAD54; RAD54L; SFM1; SHS; Transcriptional regulator ATRX; X linked helicase II; X linked nuclear protein; X-linked helicase II; X-linked nuclear protein; XH2; XNP; Znf HX; Znf-HX
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
0.7 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for ATRX Polyclonal Antibody?

The catalog number for ATRX Polyclonal Antibody is E-AB-19609.

What sizes are available for ATRX Polyclonal Antibody?

ATRX Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does ATRX Polyclonal Antibody come in?

ATRX Polyclonal Antibody is available in 4 different pack sizes.

Is ATRX Polyclonal Antibody in stock?

ATRX Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ATRX Polyclonal Antibody?

ATRX Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for ATRX Polyclonal Antibody?

Estimated delivery time for ATRX Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ATRX Polyclonal Antibody?

The safety data sheet for ATRX Polyclonal Antibody is available here: https://789.bio/eb/n5Wb5S.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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