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Product details

Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody

Catalog number E-AB-20869-01

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Price for E-AB-20869-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-20869-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2) . Phosphorylates SPZ1 (By similarity) . Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
Abbreviation
ERK 1/2 (phospho Tyr204)
UniProt
P27361, P28482
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human ERK 1/2 around the phosphorylation site of Tyr204
Target
MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Signal Transduction; Neuroscience
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43kDa
Observed Molecular Weight
44+42kDa
Citation 01
https://www.mdpi.com/article/10.3390/cells12010115
Citation 02
https://www.mdpi.com/1492614
Citation 03
https://www.dovepress.com/blockade-of-the-p2y2-receptor-attenuates-alcoholic-liver-inflammation--peer-reviewed-fulltext-article-DDDT
Isotype
IgG

Frequently Asked Questions

What is the catalog number for Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody?

The catalog number for Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody is E-AB-20869.

What sizes are available for Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody?

Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody come in?

Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody is available in 4 different pack sizes.

Is Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody in stock?

Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody?

Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody?

Estimated delivery time for Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody?

The safety data sheet for Phospho-ERK 1/2 (Tyr204) Polyclonal Antibody is available here: https://789.bio/eb/f9ezTO.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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