Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody

Catalog number E-AB-20966-01

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Price for E-AB-20966-01

Size / count 20 µL

Specifications

Catalog number: E-AB-20966-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha) . p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
Abbreviation: PI 3-kinase p85/p55 (phospho Tyr467/199)
UniProt: P27986, Q92569
Host: Rabbit
Reactivity: Human; Mouse; Rat; Monkey
Immunogen: Synthesized peptide derived from human PI 3-kinase p85/p55 around the phosphorylation site of Tyr467/199
Target: GRB1; p85 alpha; p85; P85A; Phosphatidylinositol 3 kinase associated p 85 alpha; Phosphatidylinositol 3 kinase regulatory 1; Phosphatidylinositol 3 kinase; regulatory subunit; polypeptide 1 (p85 alpha) ; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit alpha; Phosphoinositide 3 kinase; regulatory subunit 1 (alpha) ; PI3 kinase p85 subunit alpha; PI3-kinase regulatory subunit alpha; PI3-kinase subunit p85-alpha; PI3K; PI3K regulatory subunit alpha; Pik3r1; PtdIns 3 kinase p85 alpha; PtdIns-3-kinase regulatory subunit alpha; PtdIns-3-kinase regulatory subunit p85-alpha
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Cancer; Immunology; Signal Transduction
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 54+83kDa
Observed Molecular Weight: 55+85kDa
Citation 01: https://elifesciences.org/articles/79590
Citation 02: https://www.mdpi.com/1281194
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody?

The catalog number for Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody is E-AB-20966.

What sizes are available for Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody?

Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody come in?

Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody is available in 4 different pack sizes.

Is Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody in stock?

Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody?

Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody?

Estimated delivery time for Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody?

The safety data sheet for Phospho-PI 3 kinase p85 alpha /gamma (Tyr467/199) Polyclonal Antibody is available here: https://789.bio/eb/fD4KSO.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.