Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody

Catalog number E-AB-21121-01

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Price for E-AB-21121-01

Size / count 20 µL

Specifications

Catalog number: E-AB-21121-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic α subunit and regulatory β and γ subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively.
Abbreviation: AMPKα1/2 (phospho Thr183/172)
UniProt: Q13131, P54646
Host: Rabbit
Reactivity: Human; Mouse; Rat; Monkey
Immunogen: Synthesized peptide derived from human AMPKα1/2 around the phosphorylation site of Thr183/172
Target: PRKAA1; AMPK1;5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA2; AMPK
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:50-1:200
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 62kDa
Observed Molecular Weight: 63kDa
Citation 01: https://www.mdpi.com/1960060
Citation 02: https://www.mdpi.com/1907994
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody?

The catalog number for Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody is E-AB-21121.

What sizes are available for Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody?

Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody come in?

Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody is available in 4 different pack sizes.

Is Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody in stock?

Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody?

Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody?

Estimated delivery time for Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody?

The safety data sheet for Phospho-AMPK alpha1/2 (Thr183/172) Polyclonal Antibody is available here: https://789.bio/eb/1SubvL.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.