Product details

P53 Monoclonal Antibody

Catalog number E-AB-22015-01

Choose a variant (4 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-22015-01

Size / count 20 µL

Specifications

Catalog number: E-AB-22015-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
Abbreviation: P53
UniProt: P04637
Host: Mouse
Reactivity: Human
Immunogen: Synthetic Peptide
Target: Antigen NY-CO-13; BCC7; Cellular tumor antigen p53; FLJ92943; LFS1; Mutant tumor protein 53; p53; p53 tumor suppressor; P53; Phosphoprotein p53; Tp53; Transformation related protein 53; TRP53; Tumor protein 53; Tumor protein p53; Tumor suppressor p53
Clonality: Monoclonal
Clone: Clone:1H4
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Cancer; Cell Biology; Epigenetics and Nuclear Signaling
Purification: Protein A purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:100-1:200
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 44kDa
Observed Molecular Weight: 53kDa
Citation 01: https://www.mdpi.com/2218-273X/10/4/577/htm
Isotype: IgG

Frequently Asked Questions

What is the catalog number for P53 Monoclonal Antibody?

The catalog number for P53 Monoclonal Antibody is E-AB-22015.

What sizes are available for P53 Monoclonal Antibody?

P53 Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does P53 Monoclonal Antibody come in?

P53 Monoclonal Antibody is available in 4 different pack sizes.

Is P53 Monoclonal Antibody in stock?

P53 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P53 Monoclonal Antibody?

P53 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for P53 Monoclonal Antibody?

Estimated delivery time for P53 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P53 Monoclonal Antibody?

The safety data sheet for P53 Monoclonal Antibody is available here: https://789.bio/eb/S08q1C.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.