NFκB-p65 Monoclonal Antibody

Catalog number E-AB-22016-01

Choose a variant (4 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-22016-01

Size / count 20 µL

Specifications

Catalog number: E-AB-22016-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor NFκB (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp κB sequence in the immunoglobulin κ light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NFκB is activated and NFκB is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.
Abbreviation: NFkB p65
UniProt: Q04206
Host: Mouse
Reactivity: Human; Mouse
Immunogen: Synthetic Peptide
Target: Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NF kappa B p65delta3; NFKB3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; OTTHUMP00000233473; OTTHUMP00000233474; OTTHUMP00000233475; OTTHUMP00000233476; OTTHUMP00000233900; p65; p65 NF kappaB; p65 NFkB; relA; TF65; Transcription factor p65; v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65) ) ; V rel avian reticuloendotheliosis viral oncogene homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian) ; V rel reticuloendotheliosis viral oncogene homolog A; nuclear factor of kappa light polypeptide gene enhancer in B cells 3; p65
Clonality: Monoclonal
Clone: Clone:9B4
Conjugation: Unconjugated
Applications: WB
Field of Research: Cancer; Cell Biology; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Microbiology; Neuroscience; Signal Transduction
Purification: Protein A purification
Concentration: 1 mg/mL
Dilution: WB 1:1000-3000
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 60kDa
Observed Molecular Weight: 65kDa
Citation 01: https://onlinelibrary.wiley.com/doi/abs/10.1111/exd.14041
Citation 02: https://onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.13876
Isotype: IgG

Frequently Asked Questions

What is the catalog number for NFκB-p65 Monoclonal Antibody?

The catalog number for NFκB-p65 Monoclonal Antibody is E-AB-22016.

What sizes are available for NFκB-p65 Monoclonal Antibody?

NFκB-p65 Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does NFκB-p65 Monoclonal Antibody come in?

NFκB-p65 Monoclonal Antibody is available in 4 different pack sizes.

Is NFκB-p65 Monoclonal Antibody in stock?

NFκB-p65 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NFκB-p65 Monoclonal Antibody?

NFκB-p65 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for NFκB-p65 Monoclonal Antibody?

Estimated delivery time for NFκB-p65 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NFκB-p65 Monoclonal Antibody?

The safety data sheet for NFκB-p65 Monoclonal Antibody is available here: https://789.bio/eb/SqjrPK.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.