KIF7 Monoclonal Antibody

Specifications

Catalog number

E-AB-22026-01

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.

Abbreviation

Kif 7

UniProt

Q2M1P5

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic Peptide

Target

EQYK340; kif7; KIF7; kinesin family member 7; kinesin like protein KIF7; Kinesin-like protein kif7; UNQ340

Clonality

Monoclonal

Clone

Clone:3I4

Conjugation

Unconjugated

Applications

IHC-p; IF

Field of Research

Signal Transduction; Stem Cells

Purification

Protein A purification

Concentration

1 mg/mL

Dilution

IHC 1:100-1:300; IF 1:50-200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG