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Product details

IDE Monoclonal Antibody

Catalog number E-AB-22041-01

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Price for E-AB-22041-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-22041-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.
Abbreviation
IDE
UniProt
P14735
Host
Mouse
Reactivity
Human
Immunogen
Synthetic Peptide
Target
Abeta-degrading protease; FLJ35968; Ide; IDE; Insulin protease; Insulin-degrading enzyme; Insulinase; Insulysin; OTTHUMP00000020097
Clonality
Monoclonal
Clone
Clone:1H4
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Cell Biology; Cardiovascular; Metabolism; Neuroscience; Signal Transduction
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-300; IF 1:100-1:300
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight
118kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for IDE Monoclonal Antibody?

The catalog number for IDE Monoclonal Antibody is E-AB-22041.

What sizes are available for IDE Monoclonal Antibody?

IDE Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does IDE Monoclonal Antibody come in?

IDE Monoclonal Antibody is available in 4 different pack sizes.

Is IDE Monoclonal Antibody in stock?

IDE Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IDE Monoclonal Antibody?

IDE Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for IDE Monoclonal Antibody?

Estimated delivery time for IDE Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for IDE Monoclonal Antibody?

The safety data sheet for IDE Monoclonal Antibody is available here: https://789.bio/eb/ffT4eT.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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