Histone H2B Monoclonal Antibody

Catalog number E-AB-22086-01

Choose a variant (4 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-22086-01

Size / count 20 µL

Specifications

Catalog number: E-AB-22086-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN.
Abbreviation: Histone H2B
UniProt: P33778
Host: Mouse
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic Peptide
Target: HIST1H2BA; testis; bA317E16.3; H2B; H2B histone family member U; H2B histone family member U testis specific; H2B histone family; member U; (testis specific) ; H2B testis; H2B1A; H2BFU; H2BT; HIST1H2BA; Histone 1; H2ba; Histone cluster 1 H2ba; Histone H2B; Histone H2B testis; Histone H2B type 1 A; Histone H2B type 1-A; Histone H2B type 1A; STBP; Testis specific histone H2B; Testis-specific histone H2B; TSH 2B; TSH2B; TSH2B.1
Clonality: Monoclonal
Clone: Clone:3C3
Conjugation: Unconjugated
Applications: WB; IF
Field of Research: Cancer; Epigenetics and Nuclear Signaling
Purification: Protein A purification
Concentration: 1 mg/mL
Dilution: WB 1:1000-3000; IF 1:100-200
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 14kDa
Observed Molecular Weight: 14kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Histone H2B Monoclonal Antibody?

The catalog number for Histone H2B Monoclonal Antibody is E-AB-22086.

What sizes are available for Histone H2B Monoclonal Antibody?

Histone H2B Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does Histone H2B Monoclonal Antibody come in?

Histone H2B Monoclonal Antibody is available in 4 different pack sizes.

Is Histone H2B Monoclonal Antibody in stock?

Histone H2B Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Histone H2B Monoclonal Antibody?

Histone H2B Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Histone H2B Monoclonal Antibody?

Estimated delivery time for Histone H2B Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Histone H2B Monoclonal Antibody?

The safety data sheet for Histone H2B Monoclonal Antibody is available here: https://789.bio/eb/nTaHi1.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.