Catenin beta Monoclonal Antibody

Catalog number E-AB-22111-01

Choose a variant (4 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-22111-01

Size / count 20 µL

Specifications

Catalog number: E-AB-22111-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Key dowstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes.Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
Abbreviation: Catenin-β
UniProt: P35222
Host: Mouse
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant Protein
Target: Beta catenin; Beta-catenin; Cadherin associated protein; Catenin (cadherin associated protein) ; beta 1;88kDa; Catenin beta 1; Catenin beta-1; CATNB; CHBCAT; CTNB1; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289
Clonality: Monoclonal
Clone: Clone:2E4
Conjugation: Unconjugated
Applications: WB; IHC-p; IF
Field of Research: Cancer; Cardiovascular; Neuroscience; Signal Transduction; Stem Cells
Purification: Protein A purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:100-1:300
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight: 92kDa
Citation 01: https://www.frontiersin.org/articles/10.3389/fonc.2021.669560/full
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Catenin beta Monoclonal Antibody?

The catalog number for Catenin beta Monoclonal Antibody is E-AB-22111.

What sizes are available for Catenin beta Monoclonal Antibody?

Catenin beta Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does Catenin beta Monoclonal Antibody come in?

Catenin beta Monoclonal Antibody is available in 4 different pack sizes.

Is Catenin beta Monoclonal Antibody in stock?

Catenin beta Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Catenin beta Monoclonal Antibody?

Catenin beta Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Catenin beta Monoclonal Antibody?

Estimated delivery time for Catenin beta Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Catenin beta Monoclonal Antibody?

The safety data sheet for Catenin beta Monoclonal Antibody is available here: https://789.bio/eb/ufPqTS.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.