BECN1 Monoclonal Antibody — image 1 of 2

Product details

BECN1 Monoclonal Antibody

Catalog number E-AB-22139-01

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Price for E-AB-22139-01

Size / count 20 µL

Specifications

Catalog number: E-AB-22139-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Abbreviation: BECN1
UniProt: Q14457
Host: Mouse
Reactivity: Human; Mouse; Rat
Immunogen: Synthetic Peptide of Beclin-1
Target: APG6; ATG 6; ATG6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; Beclin 1 (coiled coil moesin like BCL2 interacting protein) ; Beclin 1 autophagy related; Beclin-1; Beclin1; BECN 1; Becn1; BECN1; Coiled coil myosin like BCL2 interacting protein; Coiled-coil myosin-like BCL2-interacting protein; GT197; Protein GT197; VPS 30; VPS30
Clonality: Monoclonal
Clone: Clone:3C6
Conjugation: Unconjugated
Applications: WB; IHC-p
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Metabolism; Microbiology; Signal Transduction
Purification: Protein A purification
Concentration: 1 mg/mL
Dilution: WB 1:1000-2000; IHC 1:100-200
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight: 60kDa
Citation 01: https://www.mdpi.com/2227-9059/10/5/1092
Citation 02: https://www.frontiersin.org/articles/10.3389/fonc.2019.01469/full
Isotype: IgG

Frequently Asked Questions

What is the catalog number for BECN1 Monoclonal Antibody?

The catalog number for BECN1 Monoclonal Antibody is E-AB-22139.

What sizes are available for BECN1 Monoclonal Antibody?

BECN1 Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does BECN1 Monoclonal Antibody come in?

BECN1 Monoclonal Antibody is available in 4 different pack sizes.

Is BECN1 Monoclonal Antibody in stock?

BECN1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BECN1 Monoclonal Antibody?

BECN1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for BECN1 Monoclonal Antibody?

Estimated delivery time for BECN1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BECN1 Monoclonal Antibody?

The safety data sheet for BECN1 Monoclonal Antibody is available here: https://789.bio/eb/Kin14K.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.