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Product details

ERK 1/2 Monoclonal Antibody

Catalog number E-AB-22142-01

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Price for E-AB-22142-01

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Size / count 20 µL

Specifications

Catalog number
E-AB-22142-01
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2) . Phosphorylates SPZ1 (By similarity) . Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
Abbreviation
ERK1/2 Mouse (1H4)
UniProt
P27361, P28482
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic Peptide of ERK1/2
Target
MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p
Clonality
Monoclonal
Clone
Clone:7D3
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Signal Transduction; Neuroscience
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:1000-2000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight
44,42kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for ERK 1/2 Monoclonal Antibody?

The catalog number for ERK 1/2 Monoclonal Antibody is E-AB-22142.

What sizes are available for ERK 1/2 Monoclonal Antibody?

ERK 1/2 Monoclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does ERK 1/2 Monoclonal Antibody come in?

ERK 1/2 Monoclonal Antibody is available in 4 different pack sizes.

Is ERK 1/2 Monoclonal Antibody in stock?

ERK 1/2 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ERK 1/2 Monoclonal Antibody?

ERK 1/2 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for ERK 1/2 Monoclonal Antibody?

Estimated delivery time for ERK 1/2 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ERK 1/2 Monoclonal Antibody?

The safety data sheet for ERK 1/2 Monoclonal Antibody is available here: https://789.bio/eb/av1mnH.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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